Texts explained; Fifthly, Acts 2:36. The Regula Fidei must be observed; madeapplies to our Lord's manhood; and to His manifestation; and to His office relative to us; and is relative to the Jews. Parallel instance in Genesis 27:29, 37. The context contradicts the Arianinterpretation
17 The Jews then, most of them, hearing this, came to themselves and immediately acknowledged the Christ, as it is written in the Acts. But, the Ario-maniacs on the contrary choose to remain Jews, and to contend with Peter; so let us proceed to place before them some parallel phrases; perhaps it may have some effect upon them, to find what the usage is of divine Scripture. Now that Christ is everlasting Lord and King, has become plain by what has gone before, nor is there a man to doubt about it; for being Son of God, He must be like Him, and being like, He is certainly both Lord and King, for He says Himself, 'He that has seen Me, has seen the Father.' On the other hand, that Peter's mere words, 'He has made Him both Lord and Christ,' do not imply the Son to be a creature, may be seen from Isaac's blessing, though this illustration is but a faint one for our subject. Now he said to Jacob, 'Become thou lord over your brother;' and to Esau, 'Behold, I have made him your lord. ' Now though the word 'made' had implied Jacob's essence and the coming into being, even then it would not be right in them as much as to imagine the same of the Word of God, for the Son of God is no creature as Jacob was; besides, they might inquire and so rid themselves of that extravagance. But if they do not understand it of his essence nor of his coming into being, though Jacob was by nature creature and work, is not their madness worse than the Devil's, if what they dare not ascribe in consequence of a like phrase even to things by nature originate, that they attach to the Son of God, saying that He is a creature? For Isaac said 'Become' and 'I have made,' signifying neither the coming into being nor the essence of Jacob (for after thirty years and more from his birth he said this); but his authority over his brother, which came to pass subsequently.
18. Much more then did Peter say this without meaning that the Essence of the Word was a work; for he knew Him to be God's Son, confessing, 'You are the Christ, the Son of the Living God;' but he meant His Kingdom and Lordship which was formed and came to be according to grace, and was relatively to us. For while saying this, he was not silent about the Son of God's everlasting Godhead which is the Father's; but He had said already, that He had poured the Spirit on us; now to give the Spirit with authority, is not in the power of creature or work, but the Spirit is God's Gift. For the creatures are hallowed by the Holy Spirit; but the Son, in that He is not hallowed by the Spirit, but on the contrary Himself the Giver of it to all, is therefore no creature, but true Son of the Father. And yet He who gives the Spirit, the same is said also to be made; that is, to be made among us Lord because of His manhood, while giving the Spirit because He is God's Word. For He ever was and is, as Son, so also Lord and Sovereign of all, being like in all things to the Father, and having all that is the Father's as He Himself has said.
Source: Four Discourses Against the Arians (New Advent)