The Dispute between the Empress and John. Arrival of Theophilus from Egypt. Cyrinus, Bishop of Chalcedon
After the departure of Epiphanius, John, when preaching in the church as usual, chanced to inveigh against the vices to which females are peculiarly prone. The people imagined that his strictures were enigmatically directed against the wife of the emperor. The enemies of the bishop did not fail to report his discourse in this sense to the empress; and she, conceiving herself to have been insulted, complained to the emperor, and urged the necessity for the speedy presence of Theophilus and the convocation of a council.
Severian, bishop of Gabala, who had not yet changed his former resentment against John, cooperated in the promotion of these measures. I am not in possession of sufficient data to determine whether there was any truth in the current report that John delivered the discourse above mentioned with express allusion to the empress, because he suspected her of having excited Epiphanius against him. Theophilus arrived soon after at Chalcedon in Bithynia, and was followed there by many bishops.
Some of the bishops joined him in compliance with his own invitation, and others in obedience to the commands of the emperor. The bishops whom John had deposed in Asia repaired to Chalcedon with the utmost alacrity, as likewise all those who cherished any feeling of hostility against him. The ships which Theophilus expected from Egypt had already come to Chalcedon. When they had convened again in the same place, and when they had deliberated how the attempt against John might be judiciously forwarded by them, Cyrinus, leader of the church of Chalcedon, who was an Egyptian and a relative of Theophilus, and who had besides some other difficulties with John, spoke very abusively of him.
Justice, however, seemed to follow him speedily; for Maruthas, a native of Mesopotamia, who had accompanied the bishops, happened to tread on his foot; and Cyrinus suffered so severely from this accident that he was unable to repair with the other bishops to Constantinople, although his aid was necessary to the execution of the designs that had been formed against John. The wound assumed so alarming an appearance, that the surgeons were obliged to perform several operations on the leg; and at length mortification took place, and spread over the whole body, and even extended to the other foot. He expired soon afterwards in great agony.
Source: Ecclesiastical History (New Advent)